Low-dose isotretinoin in acne vulgaris: a critical review.

نویسندگان

  • K Sardana
  • V K Garg
چکیده

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منابع مشابه

A randomized comparative trial of two low-dose oral isotretinoin regimens in moderate to severe acne vulgaris

BACKGROUND Oral isotretinoin is highly effective in all forms and grades of acne, even in lower dosages (<0.5 mg/kg/day). There is a paucity of comparative data on the various low-dose regimens of oral isotretinoin in the Indian literature. OBJECTIVES To assess and compare the efficacy and tolerability of two low-dose oral isotretinoin treatment regimens (20 mg daily and 20 mg alternate days)...

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Effects of Isotretinoin on bone density and Calcium homeostasis in patients with Acne Vulgaris

Background and aim: Side effects of long-term systemic isotretinion use with high accumulative doses on skeletal system have been known, but there are few studies about the effects of short term isotretinoin therapy for acne patients. This study was aimed to recognize the effects of systemic isotretinion on calcium homeostasis and bone density in acne patients referring to clinics affilia...

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Comparison of Low-Dose Treatment of Isotretinoin and Flutamide Combined with Oral Erythromycin for Female Patients with Severe Acne

Background & objectives: Acne is a chronic inflammation of pilosebaceous units and in severe form reflects a different response to treatment in an oral regime of antibiotics. The purpose of this study is to compare the effect of the combination of erythromycin and low dose oral isotretinoin with erythromycin and low dose flutamide in women suffering from severe acne. Methods: In a randomized co...

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Creatine phosphokinase values and myalgia during isotretinoin therapy

Background: Systemic isotretinoin is a very effective medication for the treatment of acne, but it has some side effects. One of its side effects is musculoskeletal problems such as increased levels of creatine phosphokinase (CPK), myalgia, and serious muscle damage such as rhabdomyolysis. The aim of this study was to evaluate the incidence of myalgia and its relationship with the elevation of ...

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New and emerging treatments in dermatology: acne.

Topical retinoids, benzoyl peroxide, azelaic acid, and topical and oral antibiotics remain the milestone of treatment for mild to moderate acne vulgaris. Oral isotretinoin is useful for the treatment of severe nodular acne, treatment-resistant acne, and acne with a risk of physical or psychological scarring. Hormonal treatment in female acne is useful in resistant or late-onset acne. With incre...

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عنوان ژورنال:
  • The British journal of dermatology

دوره 165 3  شماره 

صفحات  -

تاریخ انتشار 2011